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Overview

Colonoscopy is a procedure used to examine the lining of the rectum and colon, which together form the large intestine. A thin, flexible tube with a light and camera is passed through the anus and guided through the colon.

Colonoscopy can detect polyps, cancers, inflammation, bleeding and other abnormalities. Tissue samples can be taken, and many polyps can be removed during the same procedure.

It is used for colorectal cancer screening, investigation of symptoms, diagnosis, surveillance and selected treatments. CT, MRI, PET-CT or other tests may still be required to determine whether a cancer has spread beyond the bowel.

Colonoscopy
How the Technology Works
Colonoscopy provides a real-time view of the inner surface of the rectum and colon. Instruments can be passed through the colonoscope to collect tissue or perform selected treatments.
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Flexible Colonoscope
A thin, flexible colonoscope is passed through the anus and guided through the rectum and colon. A camera at its tip sends magnified images to a monitor.
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Direct Visualisation
Air or carbon dioxide is introduced gently to expand the colon and improve visibility. The doctor examines the lining for polyps, masses, ulcers, inflammation, narrowing, bleeding and other changes.
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Biopsy and Treatment Channels
Small instruments can be passed through channels within the colonoscope to take biopsies or remove polyps. The same channels may be used to control bleeding, mark a lesion, remove selected early lesions or place a stent when appropriate.

Role in Cancer Care

Colorectal Cancer Screening
Colonoscopy may be used to screen people who do not have bowel symptoms. It can detect colorectal cancer at an earlier stage and identify precancerous polyps before they become cancerous. Screening age and frequency depend on individual risk and the guidelines followed by the treating centre.
Colorectal Cancer Screening
Following an Abnormal Screening Test
Colonoscopy is usually required after a positive or abnormal stool-based colorectal cancer screening test. It allows the doctor to locate the source of the abnormal result, remove polyps and take biopsies. A positive stool test does not by itself confirm cancer.
Following an Abnormal Screening Test
Investigating Symptoms
Colonoscopy may be recommended for rectal bleeding, unexplained iron-deficiency anemia, persistent changes in bowel habits, abdominal pain or unexplained weight loss. These symptoms can have many non-cancerous causes. Direct examination helps identify abnormalities that may require biopsy or treatment.
Investigating Symptoms
Detecting and Removing Polyps
Many colorectal cancers develop from precancerous polyps, including certain adenomas and serrated lesions. Colonoscopy allows these growths to be found and removed during the same procedure. The removed tissue is examined by a pathologist to determine its type and whether further treatment or surveillance is required.
Detecting and Removing Polyps
Diagnosing and Localising Cancer
If a suspicious mass or abnormal area is found, tissue samples can be collected for pathological examination. Colonoscopy can document the tumour’s position and visible extent within the bowel and may be used to mark the site for surgery. It cannot fully determine how deeply the tumour has grown or whether it has spread beyond the colon.
Diagnosing and Localising Cancer
Treatment and Follow-up
Selected superficial cancers may be removed using advanced endoscopic techniques. Colonoscopy may also control bleeding or place a stent across an obstruction in appropriately selected patients. After treatment, it may be used to examine the bowel for new polyps, recurrent disease or changes at a surgical connection.
Treatment and Follow-up

What to Expect

Before the Test

The colon must be thoroughly cleaned so that the lining can be examined clearly. Inadequate bowel preparation can hide polyps or cancers and may require the procedure to be repeated.

You will receive specific instructions that may include:

  • Temporarily following a low-fibre diet

  • Changing to clear liquids before the procedure

  • Taking a prescribed laxative solution, usually in divided doses

  • Avoiding certain coloured liquids

  • Stopping all food and drink at the specified time

The bowel preparation will cause frequent watery bowel movements, so remain close to a toilet. Complete the preparation exactly as instructed, even when the bowel movements appear clear.

Inform the care team if you:

  • Take blood thinners, aspirin or medicines that affect clotting

  • Have diabetes and use insulin or other glucose-lowering medicines

  • Have heart, lung, kidney or liver disease

  • Have constipation, bowel obstruction symptoms or previous bowel surgery

  • Have allergies or have previously reacted to sedation or anesthesia

  • Are pregnant or may be pregnant

  • Take prescription medicines, non-prescription medicines or supplements

  • Have a pacemaker or another implanted device

Do not stop or adjust medicines unless specifically instructed. The type and amount of bowel preparation may need to be modified for people with certain kidney, heart or electrolyte conditions.

If sedation or anesthesia will be used, arrange for a responsible adult to accompany you home. You should not drive after the procedure.

Before the Test

During the Test

You will usually lie on your side. Sedation, anesthesia or pain medicine may be given through a vein to keep you comfortable.

The doctor inserts the colonoscope through the anus and guides it through the rectum and colon. Air or carbon dioxide is introduced to expand the bowel, and water may also be used to improve visualisation.

The doctor slowly withdraws the colonoscope while carefully examining the bowel lining. Your position may be changed, or gentle pressure may be applied to the abdomen to help the scope pass safely.

Polyps may be removed, and biopsies can be taken without causing cutting pain within the bowel lining. Larger or complex lesions may require an advanced procedure or a separate treatment session.

A routine colonoscopy commonly takes approximately 30 to 60 minutes. It may take longer if multiple polyps are removed or another treatment is performed.

During the Test

After the Test

You will be monitored until the effects of sedation or anesthesia have reduced. Bloating, cramping or increased gas may occur temporarily because of the air introduced during the procedure.

If sedation was used, do not drive, operate machinery, drink alcohol, sign important documents or make major decisions for the period specified by the care team. Arrange for someone to accompany you and stay with you if advised.

You can usually resume eating according to the instructions provided. If a large polyp or lesion was removed, temporary dietary, medicine or activity restrictions may be recommended.

The doctor may discuss the visual findings after the procedure. Polyp and biopsy results take longer because the tissue must be processed and examined by a pathologist.

A small amount of rectal bleeding can occur after a biopsy or polyp removal. Seek urgent medical attention if you develop:

  • Severe or worsening abdominal pain

  • Fever

  • Persistent vomiting

  • A swollen or rigid abdomen

  • Heavy or persistent rectal bleeding

  • Black stools

  • Dizziness, marked weakness or fainting

  • Breathing difficulty or chest pain

Bleeding can occasionally occur several days after a polyp is removed. Follow the specific instructions provided by the endoscopy team.

After the Test

Potential Benefits

Colonoscopy combines direct examination, tissue sampling and polyp removal during the same procedure.
  • Cancer prevention: Precancerous polyps can be identified and removed.
  • Early detection: Colorectal cancer may be detected before it causes symptoms.
  • Direct visualisation: The lining of the rectum and colon can be examined in real time.
  • Tissue diagnosis: Biopsies can be taken directly from suspicious areas.
  • Polyp removal: Many polyps can be removed during the examination.
  • Accurate localisation: The location of a tumour or lesion can be documented or marked for treatment.
  • Diagnostic and therapeutic use: Bleeding, selected early lesions or obstruction may be treated endoscopically in suitable patients.
  • Surveillance: The colon can be monitored after polyp removal or colorectal cancer treatment.
Colonoscopy
Frequently Asked Questions
01 When should colorectal cancer screening begin?
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The recommended age and screening interval vary according to the guideline followed and individual risk. In India, screening usually begins from age 50. People with a family history of colorectal cancer, previous polyps, inflammatory bowel disease or an inherited cancer syndrome may need earlier or more frequent screening. A healthcare professional can recommend an appropriate plan.
02 Why is bowel preparation so important?
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Stool can hide polyps, flat lesions and cancers from view. Thorough preparation improves the quality and completeness of the examination. If preparation is inadequate, the colonoscopy may need to be repeated sooner or on another day.
03 Is colonoscopy painful?
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Sedation, anesthesia or pain medicine is commonly used, so many people experience little or no discomfort during the procedure. Temporary pressure, cramping, bloating or gas may occur. The approach to sedation varies according to the patient, procedure and centre.
04 Does every polyp become cancerous?
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No. Many polyps never become cancer, but certain adenomatous and serrated polyps can develop into cancer over time. Removed polyps are examined by a pathologist, and their type, size, number and features help determine the follow-up interval.
05 Can colonoscopy confirm colorectal cancer?
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Colonoscopy can identify a suspicious lesion and provide tissue samples. Cancer is confirmed by pathological examination of the biopsy or removed tissue rather than by appearance alone. If initial biopsies are inconclusive, further sampling may occasionally be required.
06 What are the possible complications?
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Colonoscopy is generally safe, but complications can include bleeding, perforation of the bowel or a reaction to sedation or anesthesia. The risk is higher when a large polyp or lesion is removed. Your doctor will explain the risks relevant to the planned procedure.
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